Fingolimod

Monitoring
Fingolimod works by sequestering lymphocytes in lymph nodes. Because of this, it is normal for the blood lymphocyte count to fall; the drug information sheets suggest 0.2 as a lower limit for safety, and the scientific literature broadly agrees.

Risks
Serious risks: macular oedema, bradycardia, rebound after stopping

Links

 * BNF entry
 * Summary of Product Characteristics (SmPC)
 * Cochrane review 2016